What Is Epithalon? Telomerase & Longevity Peptide Research Guide
An overview of Epithalon — a synthetic pineal-derived tetrapeptide — covering how it is studied in telomerase and ageing research, and its research-use-only status in the UK.
7 min read · Published 2026-06-23
What Is Epithalon?
Epithalon (also written epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) modelled on epithalamin, a peptide extract of the pineal gland. It was developed in Russia and is studied in the context of ageing biology.
Research use only. This material is supplied for in-vitro laboratory research. It is not a medicine and is not for human or veterinary consumption, administration, or therapeutic use.
How Epithalon Is Studied to Work
In research Epithalon is associated with effects on telomerase activity, telomere maintenance and circadian/melatonin regulation in cell and animal models. These findings have made it a focus of longevity research.
Evidence & Regulatory Status
Much of the Epithalon literature originates from Russian laboratories, and independent large-scale validation is limited. Epithalon is not approved as a medicine by the MHRA and is supplied for laboratory research only.
Research Handling & Quality
As a lyophilised (freeze-dried) peptide it is typically stored frozen and reconstituted with bacteriostatic water for in-vitro work — see our reconstitution guide and storage guide. Identity and purity should be verified against a batch-matched Certificate of Analysis (COA) with HPLC and mass-spectrometry data. View epithalon product details and COA.
Frequently Asked Questions
Is Epithalon approved in the UK?
No. Epithalon is supplied for laboratory research use only and has no UK marketing authorisation.
What is Epithalon studied for?
It is examined for effects on telomerase activity and circadian regulation in laboratory ageing-research models.
Is Epithalon the same as epitalon?
Yes — 'Epithalon' and 'epitalon' are alternative spellings of the same Ala-Glu-Asp-Gly tetrapeptide.
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