Written by the AllMyPeptides Research Team
Storage Overview
Proper storage is critical for maintaining peptide stability and ensuring accurate research results. Peptides are sensitive molecules that can degrade when exposed to heat, light, moisture, or improper pH. This guide covers the storage requirements for both lyophilised (powder) and reconstituted (liquid) forms.
All peptides supplied by AllMyPeptides are shipped in lyophilised form unless otherwise stated. Lyophilisation (freeze-drying) removes water content, which significantly extends shelf life and improves stability during shipping.
Lyophilised Peptide Storage
Lyophilised peptides should be stored at -20°C (freezer) for long-term storage up to 2 years. Short-term storage at 2-8°C (refrigerator) is acceptable for up to 6 months. Always protect from light and moisture. The vial should remain sealed until ready for use.
Reconstituted Peptide Storage
Once reconstituted with bacteriostatic water, peptides should be stored at 2-8°C (refrigerator) and used within 30 days. Do not freeze reconstituted peptides — this causes aggregation and degradation. Use sterile technique during reconstitution to prevent bacterial contamination.
Factors That Affect Peptide Stability
Several environmental factors can accelerate peptide degradation:
- Temperature: Higher temperatures increase molecular motion and chemical reactions that break peptide bonds. Always store at recommended temperatures.
- Light: UV light can cause photochemical degradation. Store peptides in opaque containers or amber vials.
- Moisture: Water enables hydrolysis reactions that cleave peptide bonds. Lyophilised peptides must stay dry.
- pH: Extreme pH values can cause acid- or base-catalysed hydrolysis. Most peptides are stable at pH 6-7.
- Oxidation: Peptides containing cysteine or methionine are susceptible to oxidation. Minimize air exposure.
Storage Best Practices
Follow these best practices to maximise peptide stability:
- Store lyophilised peptides at -20°C in a frost-free freezer
- Use aliquots to avoid repeated freeze-thaw cycles
- Allow vials to reach room temperature before opening to prevent condensation
- Reconstitute with bacteriostatic water, not sterile water
- Label vials with reconstitution date and initial concentration
- Store reconstituted peptides at 2-8°C, never at room temperature
- Use within 30 days of reconstitution
Frequently Asked Questions
How long do lyophilised peptides last?+
Can I freeze reconstituted peptides?+
What happens if I store peptides at room temperature?+
Should I use bacteriostatic water or sterile water?+
Related Guides
Products discussed in this guide are for research and laboratory use only. AllMyPeptides does not condone or support misuse of any research materials. Not for human or animal consumption.