IGF-1 LR3

Insulin-like Growth Factor-1 Long Arg3 (IGF-1 LR3) is a synthetic analogue of IGF-1 featuring an arginine substitution at position 3 and a 13-amino-acid N-terminal extension. These modifications significantly reduce IGF-1 LR3's binding to IGF binding proteins while maintaining high affinity for the IGF-1 receptor, making it a powerful research tool for studying cell proliferation, differentiation, and survival signalling pathways. Research applications span muscle cell biology, tissue regeneration models, and investigations into the IGF-1/PI3K/Akt/mTOR signalling cascade. The LR3 modification provides enhanced biological activity and extended half-life in research models compared to native IGF-1. AllMyPeptides supplies IGF-1 LR3 as a lyophilised research peptide with independent HPLC purity verification of 99%+ by independent third-party laboratories.