Understanding the Language of Peptides
The world of research peptides comes with its own vocabulary, and for a newcomer the terminology can be a barrier to making informed decisions. This glossary explains the terms encountered most often — on product pages, Certificates of Analysis, and supplier websites — in plain English. Understanding this language makes it far easier to compare products and assess quality with confidence.
Peptide
A peptide is a short chain of amino acids linked together. Amino acids are the building blocks of proteins; when a small number of them are joined in sequence, the result is a peptide. Research peptides are synthetic versions produced for laboratory study, each with a defined amino acid sequence.
Lyophilised
Lyophilised means freeze-dried. Research peptides are supplied as a lyophilised powder because they are far more stable in this dry form than in solution. The powder must be reconstituted with bacteriostatic water before use.
Reconstitution
Reconstitution is the process of dissolving a lyophilised peptide powder into a liquid by adding bacteriostatic water. The volume of water added determines the concentration of the resulting solution.
Bacteriostatic Water
Bacteriostatic water is sterile water containing a small amount of benzyl alcohol, an agent that inhibits bacterial growth. It is the preferred diluent for reconstituting peptides because it allows the solution to be stored for several weeks.
HPLC
HPLC (high-performance liquid chromatography) is the analytical technique used to measure a peptide's purity. It separates the components of a sample and quantifies the proportion that is the target peptide, producing the purity percentage stated on a Certificate of Analysis.
Mass Spectrometry
Mass spectrometry is the technique used to confirm a peptide's identity by measuring its molecular weight. If the measured mass matches the expected mass for the peptide's sequence, its identity is verified.
Certificate of Analysis (COA)
A Certificate of Analysis (COA) is a document issued by an independent laboratory recording a peptide's identity, purity, and the testing methods used. A batch-matched COA is specific to the exact batch received, rather than a generic document.
Purity
Purity is the proportion of a sample that is the target peptide, expressed as a percentage and measured by HPLC. High-quality research peptides are typically ≥98% or ≥99% pure, with the remainder being impurities such as truncated sequences.
RUO (Research Use Only)
RUO stands for Research Use Only. It indicates that a product is intended solely for laboratory research and is not for human or animal consumption. All research peptides are sold on this basis.
Blend
A blend is a research product combining two or more peptides in a single vial. The Wolverine blend, which pairs BPC-157 with TB-500, is a well-known example, allowing two complementary mechanisms to be studied together.
Frequently Asked Questions
What does lyophilised mean?
What does RUO mean?
What is a COA?
What is the difference between HPLC and mass spectrometry?
Related Guides
Products discussed in this guide are for research and laboratory use only. AllMyPeptides does not condone or support misuse of any research materials. Not for human or animal consumption.
