What Is KPV? Anti-Inflammatory Tripeptide Research Guide
An overview of KPV — the Lys-Pro-Val tripeptide — covering how it is studied in inflammation and tissue research, and its research-use-only status in the UK.
7 min read · Published 2026-06-23
What Is KPV?
KPV is a tripeptide (lysine-proline-valine) that corresponds to the C-terminal fragment of alpha-melanocyte-stimulating hormone (α-MSH). It is studied for its anti-inflammatory properties independent of pigmentation activity.
Research use only. This material is supplied for in-vitro laboratory research. It is not a medicine and is not for human or veterinary consumption, administration, or therapeutic use.
How KPV Is Studied to Work
In research KPV is associated with down-modulation of pro-inflammatory signalling and has been examined in cell and animal models of inflammation, including gastrointestinal (inflammatory bowel) models and wound-healing contexts. It is studied for its small size and stability.
Evidence & Regulatory Status
The KPV evidence base is preclinical, with limited human data. KPV is not approved as a medicine by the MHRA and is supplied for laboratory research only.
Research Handling & Quality
As a lyophilised (freeze-dried) peptide it is typically stored frozen and reconstituted with bacteriostatic water for in-vitro work — see our reconstitution guide and storage guide. Identity and purity should be verified against a batch-matched Certificate of Analysis (COA) with HPLC and mass-spectrometry data. View kpv product details and COA.
Frequently Asked Questions
Is KPV approved in the UK?
No. KPV is supplied for laboratory research use only and has no UK marketing authorisation.
Where does KPV come from?
It is the C-terminal tripeptide fragment (Lys-Pro-Val) of alpha-MSH, studied for anti-inflammatory properties.
Is KPV related to BPC-157?
They are different peptides but both are studied in tissue and inflammation research; KPV is often examined alongside compounds like BPC-157 and TB-500.
Related Guides
- What Is BPC-157? Research, Mechanisms & Where to Buy in the UK
- What Is LL-37? Antimicrobial Peptide Research Guide
- What Is a Certificate of Analysis (COA)? How to Read One
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